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Monosialoganglioside-GM1 triggers binding of the amyloid-protein salmon calcitonin to a Langmuir membrane model mimicking the occurrence of lipid-rafts

GM1 ganglioside is known to be involved in the amyloid-associated diseases and it is a crucial factor for the assembly of amyloid proteins on lipid-rafts, which are lipid structures located on the synaptic plasma membranes. Due to its slow aggregation rate, we employed salmon calcitonin (sCT) as a s...

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Detalles Bibliográficos
Autores principales: Diociaiuti, Marco, Giordani, Cristiano, Kamel, Gihan S., Brasili, Francesco, Sennato, Simona, Bombelli, Cecilia, Meneses, Karen Y., Giraldo, Marco A., Bordi, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614544/
https://www.ncbi.nlm.nih.gov/pubmed/28955978
http://dx.doi.org/10.1016/j.bbrep.2016.10.005