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Host proteostasis modulates influenza evolution

Predicting and constraining RNA virus evolution require understanding the molecular factors that define the mutational landscape accessible to these pathogens. RNA viruses typically have high mutation rates, resulting in frequent production of protein variants with compromised biophysical properties...

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Detalles Bibliográficos
Autores principales: Phillips, Angela M, Gonzalez, Luna O, Nekongo, Emmanuel E, Ponomarenko, Anna I, McHugh, Sean M, Butty, Vincent L, Levine, Stuart S, Lin, Yu-Shan, Mirny, Leonid A, Shoulders, Matthew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614556/
https://www.ncbi.nlm.nih.gov/pubmed/28949290
http://dx.doi.org/10.7554/eLife.28652