Development of a primary microglia screening assay and its use to characterize inhibition of system x(c)(-) by erastin and its analogs

The inflammatory response in the central nervous system involves activated microglia. Under normal conditions they remove damaged neurons by phagocytosis. On the other hand, neurodegenerative diseases are thought to involve chronic microglia activation resulting in release of excess glutamate, proin...

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Detalles Bibliográficos
Autores principales: Figuera-Losada, Mariana, Thomas, Ajit G., Stathis, Marigo, Stockwell, Brent R., Rojas, Camilo, Slusher, Barbara S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614578/
https://www.ncbi.nlm.nih.gov/pubmed/28956014
http://dx.doi.org/10.1016/j.bbrep.2016.12.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614578/
https://www.ncbi.nlm.nih.gov/pubmed/28956014
http://dx.doi.org/10.1016/j.bbrep.2016.12.009

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