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Development of a primary microglia screening assay and its use to characterize inhibition of system x(c)(-) by erastin and its analogs
The inflammatory response in the central nervous system involves activated microglia. Under normal conditions they remove damaged neurons by phagocytosis. On the other hand, neurodegenerative diseases are thought to involve chronic microglia activation resulting in release of excess glutamate, proin...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614578/ https://www.ncbi.nlm.nih.gov/pubmed/28956014 http://dx.doi.org/10.1016/j.bbrep.2016.12.009 |