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Blood brain barrier permeability of (−)-epigallocatechin gallate, its proliferation-enhancing activity of human neuroblastoma SH-SY5Y cells, and its preventive effect on age-related cognitive dysfunction in mice

BACKGROUND: The consumption of green tea catechins (GTCs) suppresses age-related cognitive dysfunction in mice. GTCs are composed of several catechins, of which epigallocatechin gallate (EGCG) is the most abundant, followed by epigallocatechin (EGC). Orally ingested EGCG is hydrolyzed by intestinal...

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Detalles Bibliográficos
Autores principales: Pervin, Monira, Unno, Keiko, Nakagawa, Aimi, Takahashi, Yuu, Iguchi, Kazuaki, Yamamoto, Hiroyuki, Hoshino, Minoru, Hara, Aya, Takagaki, Akiko, Nanjo, Fumio, Minami, Akira, Imai, Shinjiro, Nakamura, Yoriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614586/
https://www.ncbi.nlm.nih.gov/pubmed/28956003
http://dx.doi.org/10.1016/j.bbrep.2016.12.012