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Thermal stability of pepsin: A predictive thermodynamic model of a multi-domain protein
Pepsin is generally used in the preparation of F(ab)(2) fragments from antibodies. The antibodies that are one of the largest and fastest growing categories of bio- pharmaceutical candidates. Differential scanning calorimetric is principally suitable method to follow the energetics of a multi-domain...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614592/ https://www.ncbi.nlm.nih.gov/pubmed/28956016 http://dx.doi.org/10.1016/j.bbrep.2017.01.005 |