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Fluid shear stress applied by orbital shaking induces MG-63 osteosarcoma cells to activate ERK in two phases through distinct signaling pathways

Fluid shear stress (FSS) induces a series of biochemical responses in osteoblasts, and this “mechanoresponse” regulates their survival, proliferation and differentiation. However, the events in cells immediately after FSS application are unclear, and how biochemical signals from soluble factors modi...

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Detalles Bibliográficos
Autores principales: Fukada, Takashi, Sakajiri, Hiroki, Kuroda, Mito, Kioka, Noriyuki, Sugimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614596/
https://www.ncbi.nlm.nih.gov/pubmed/28956013
http://dx.doi.org/10.1016/j.bbrep.2017.01.004