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Fluid shear stress applied by orbital shaking induces MG-63 osteosarcoma cells to activate ERK in two phases through distinct signaling pathways
Fluid shear stress (FSS) induces a series of biochemical responses in osteoblasts, and this “mechanoresponse” regulates their survival, proliferation and differentiation. However, the events in cells immediately after FSS application are unclear, and how biochemical signals from soluble factors modi...
Autores principales: | Fukada, Takashi, Sakajiri, Hiroki, Kuroda, Mito, Kioka, Noriyuki, Sugimoto, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614596/ https://www.ncbi.nlm.nih.gov/pubmed/28956013 http://dx.doi.org/10.1016/j.bbrep.2017.01.004 |
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