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Structural insights into substrate selectivity of ribosomal RNA methyltransferase RlmCD

RlmCD has recently been identified as the S-adenosyl methionine (SAM)-dependent methyltransferase responsible for the formation of m(5)U at U747 and U1939 of 23S ribosomal RNA in Streptococcus pneumoniae. In this research, we determine the high-resolution crystal structures of apo-form RlmCD and its...

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Detalles Bibliográficos
Autores principales: Jiang, Yiyang, Li, Fudong, Wu, Jihui, Shi, Yunyu, Gong, Qingguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614603/
https://www.ncbi.nlm.nih.gov/pubmed/28949991
http://dx.doi.org/10.1371/journal.pone.0185226