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Structural insights into substrate selectivity of ribosomal RNA methyltransferase RlmCD
RlmCD has recently been identified as the S-adenosyl methionine (SAM)-dependent methyltransferase responsible for the formation of m(5)U at U747 and U1939 of 23S ribosomal RNA in Streptococcus pneumoniae. In this research, we determine the high-resolution crystal structures of apo-form RlmCD and its...
Autores principales: | Jiang, Yiyang, Li, Fudong, Wu, Jihui, Shi, Yunyu, Gong, Qingguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614603/ https://www.ncbi.nlm.nih.gov/pubmed/28949991 http://dx.doi.org/10.1371/journal.pone.0185226 |
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