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Macrophage ubiquitin-specific protease 2 modifies insulin sensitivity in obese mice

We previously reported that ubiquitin-specific protease (USP) 2 in macrophages down-regulates genes associated with metabolic diseases, suggesting a putative anti-diabetic role for USP2 in macrophages. In this study, we evaluate this role at both cellular and individual levels. Isolated macrophages...

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Detalles Bibliográficos
Autores principales: Saito, Natsuko, Kimura, Shunsuke, Miyamoto, Tomomi, Fukushima, Sanae, Amagasa, Misato, Shimamoto, Yoshinori, Nishioka, Chieko, Okamoto, Shiki, Toda, Chitoku, Washio, Kohei, Asano, Atsushi, Miyoshi, Ichiro, Takahashi, Eiki, Kitamura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614627/
https://www.ncbi.nlm.nih.gov/pubmed/28956020
http://dx.doi.org/10.1016/j.bbrep.2017.01.009