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Macrophage ubiquitin-specific protease 2 modifies insulin sensitivity in obese mice
We previously reported that ubiquitin-specific protease (USP) 2 in macrophages down-regulates genes associated with metabolic diseases, suggesting a putative anti-diabetic role for USP2 in macrophages. In this study, we evaluate this role at both cellular and individual levels. Isolated macrophages...
Autores principales: | Saito, Natsuko, Kimura, Shunsuke, Miyamoto, Tomomi, Fukushima, Sanae, Amagasa, Misato, Shimamoto, Yoshinori, Nishioka, Chieko, Okamoto, Shiki, Toda, Chitoku, Washio, Kohei, Asano, Atsushi, Miyoshi, Ichiro, Takahashi, Eiki, Kitamura, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614627/ https://www.ncbi.nlm.nih.gov/pubmed/28956020 http://dx.doi.org/10.1016/j.bbrep.2017.01.009 |
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