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IL-10-mediated signals act as a switch for lymphoproliferation in Human T-cell leukemia virus type-1 infection by activating the STAT3 and IRF4 pathways

Human T-cell leukemia virus type-1 (HTLV-1) causes two distinct diseases, adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Since there are no disease-specific differences among HTLV-1 strains, the etiological mechanisms separating these re...

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Detalles Bibliográficos
Autores principales: Sawada, Leila, Nagano, Yoshiko, Hasegawa, Atsuhiko, Kanai, Hikari, Nogami, Kai, Ito, Sayaka, Sato, Tomoo, Yamano, Yoshihisa, Tanaka, Yuetsu, Masuda, Takao, Kannagi, Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614654/
https://www.ncbi.nlm.nih.gov/pubmed/28910419
http://dx.doi.org/10.1371/journal.ppat.1006597