Cargando…

Stochastic principles governing alternative splicing of RNA

The dominance of the major transcript isoform relative to other isoforms from the same gene generated by alternative splicing (AS) is essential to the maintenance of normal cellular physiology. However, the underlying principles that determine such dominance remain unknown. Here, we analyzed the phy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Jianfei, Boritz, Eli, Wylie, William, Douek, Daniel C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614656/ https://www.ncbi.nlm.nih.gov/pubmed/28910283 http://dx.doi.org/10.1371/journal.pcbi.1005761

Ejemplares similares

Stochastic alternative splicing is prevalent in mungbean (Vigna radiata)
por: Satyawan, Dani, et al.
Publicado: (2016)

Alternative splicing regulates stochastic NLRP3 activity
por: Hoss, Florian, et al.
Publicado: (2019)

Hidden RNA pairings counteract the “first-come, first-served” splicing principle to drive stochastic choice in Dscam1 splice variants
por: Dong, Haiyang, et al.
Publicado: (2022)

Stochastic Variation in DNA Methylation Modulates Nucleosome Occupancy and Alternative Splicing in Arabidopsis thaliana
por: Jabre, Ibtissam, et al.
Publicado: (2022)

The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes
por: Montañés-Agudo, Pablo, et al.
Publicado: (2023)

Structural implication of splicing stochastics
por: Melamud, Eugene, et al.
Publicado: (2009)

Stochastic noise in splicing machinery
por: Melamud, Eugene, et al.
Publicado: (2009)

Variational principles for stochastic fluid dynamics
por: Holm, Darryl D.
Publicado: (2015)

Evolution of Alternative Splicing Regulation: Changes in Predicted Exonic Splicing Regulators Are Not Associated with Changes in Alternative Splicing Levels in Primates
por: Irimia, Manuel, et al.
Publicado: (2009)

Functional and evolutionary analysis of alternatively spliced genes is consistent with an early eukaryotic origin of alternative splicing
por: Irimia, Manuel, et al.
Publicado: (2007)

Cell-to-cell variability of alternative RNA splicing
por: Waks, Zeev, et al.
Publicado: (2011)

Alternative Promoters Influence Alternative Splicing at the Genomic Level
por: Xin, Dedong, et al.
Publicado: (2008)

Cross-kingdom patterns of alternative splicing and splice recognition
por: McGuire, Abigail M, et al.
Publicado: (2008)

Differential Recruitment of Pre-mRNA Splicing Factors to Alternatively Spliced Transcripts In Vivo
por: Mabon, Stephen A, et al.
Publicado: (2005)

SpliceInfo: an information repository for mRNA alternative splicing in human genome
por: Huang, Hsien-Da, et al.
Publicado: (2005)

Alternative RNA Splicing in the Pathogenesis of Liver Disease
por: Webster, Nicholas J. G.
Publicado: (2017)

Alternative mRNA Splicing: Control by Combination
Publicado: (2005)

Alternative mRNA Splicing in the Pathogenesis of Obesity
por: Wong, Chi-Ming, et al.
Publicado: (2018)

Alternative RNA Splicing in Fatty Liver Disease
por: Wu, Panyisha, et al.
Publicado: (2021)

Alternative Splicing of TAF6: Downstream Transcriptome Impacts and Upstream RNA Splice Control Elements
por: Kamtchueng, Catherine, et al.
Publicado: (2014)

Intron mis-splicing: no alternative?
por: Roy, Scott William, et al.
Publicado: (2008)

Autophagy regulation by RNA alternative splicing and implications in human diseases
por: González-Rodríguez, Patricia, et al.
Publicado: (2022)

Splicing and alternative splicing in rice and humans
por: E, Zhiguo, et al.
Publicado: (2013)

Strategies for Identifying RNA Splicing Regulatory Motifs and Predicting Alternative Splicing Events
por: Holste, Dirk, et al.
Publicado: (2008)

Inference of alternative splicing from RNA-Seq data with probabilistic splice graphs
por: LeGault, Laura H., et al.
Publicado: (2013)

MicroRNA-Mediated Obstruction of Stem-loop Alternative Splicing (MIMOSAS): a global mechanism for the regulation of alternative splicing
por: Zhai, Rong, et al.
Publicado: (2023)

Corepressor diversification by alternative mRNA splicing is species specific
por: Privalsky, Martin L., et al.
Publicado: (2016)

Abnormal global alternative RNA splicing in COVID-19 patients
por: Wang, Changli, et al.
Publicado: (2022)

The Emergence of Alternative 3′ and 5′ Splice Site Exons from Constitutive Exons
por: Koren, Eli, et al.
Publicado: (2007)

Prediction of alternative pre-mRNA splicing outcomes
por: Najjar, Rayan, et al.
Publicado: (2023)

RNA editing enzyme ADAR1 governs the circadian expression of P-glycoprotein in human renal cells by regulating alternative splicing of the ABCB1 gene
por: Omata, Yuji, et al.
Publicado: (2021)

RNA-Seq analysis of splicing in Plasmodium falciparum uncovers new splice junctions, alternative splicing and splicing of antisense transcripts
por: Sorber, Katherine, et al.
Publicado: (2011)

Alternative Splice in Alternative Lice
por: Tovar-Corona, Jaime M., et al.
Publicado: (2015)

miRNA-Based Regulation of Alternative RNA Splicing in Metazoans
por: Schorr, Anna L., et al.
Publicado: (2021)

Alternative Splicing and Extensive RNA Editing of Human TPH2 Transcripts
por: Grohmann, Maik, et al.
Publicado: (2010)

Alternative Splicing, RNA Editing, and the Current Limits of Next Generation Sequencing
por: Piazzi, Manuela, et al.
Publicado: (2023)

Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome
por: Fumagalli, Debora, et al.
Publicado: (2015)

Protein Modularity of Alternatively Spliced Exons Is Associated with Tissue-Specific Regulation of Alternative Splicing
por: Xing, Yi, et al.
Publicado: (2005)

What are the principles that govern life?
por: Gómez-Márquez, Jaime
Publicado: (2020)

Principles Governing Malleting Force
Publicado: (1897)

Cannot write session to /tmp/vufind_sessions/sess_lbom5k7etq8apusevgn6udleie