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Bioengineered Bruch's-like extracellular matrix promotes retinal pigment epithelial differentiation

In the eye, the retinal pigment epithelium (RPE) adheres to a complex protein matrix known as Bruch's membrane (BrM). The aim of this study was to provide enriched conditions for RPE cell culture through the production of a BrM-like matrix. Our hypothesis was that a human RPE cell line would de...

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Detalles Bibliográficos
Autores principales: McLenachan, Samuel, Hao, Erwei, Zhang, Dan, Zhang, Ling, Edel, Michael, Chen, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614661/
https://www.ncbi.nlm.nih.gov/pubmed/28955745
http://dx.doi.org/10.1016/j.bbrep.2017.03.008