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Bioengineered Bruch's-like extracellular matrix promotes retinal pigment epithelial differentiation
In the eye, the retinal pigment epithelium (RPE) adheres to a complex protein matrix known as Bruch's membrane (BrM). The aim of this study was to provide enriched conditions for RPE cell culture through the production of a BrM-like matrix. Our hypothesis was that a human RPE cell line would de...
Autores principales: | McLenachan, Samuel, Hao, Erwei, Zhang, Dan, Zhang, Ling, Edel, Michael, Chen, Fred |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614661/ https://www.ncbi.nlm.nih.gov/pubmed/28955745 http://dx.doi.org/10.1016/j.bbrep.2017.03.008 |
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