Visualization of ceramide channels in lysosomes following endogenous palmitoyl-ceramide accumulation as an initial step in the induction of necrosis

In this study, we showed that the dual addition of glucosyl ceramide synthase and ceramidase inhibitors to A549 cell culture led to the possibility of ceramide channel formation via endogenous palmitoyl-ceramide accumulation with an increase in cholesterol contents in the lysosome membrane as an ini...

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Detalles Bibliográficos
Autores principales: Yamane, Mototeru, Moriya, Shota, Kokuba, Hiroko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614681/
https://www.ncbi.nlm.nih.gov/pubmed/28955782
http://dx.doi.org/10.1016/j.bbrep.2017.02.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614681/
https://www.ncbi.nlm.nih.gov/pubmed/28955782
http://dx.doi.org/10.1016/j.bbrep.2017.02.010

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