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Is the prognostic significance of O6-methylguanine- DNA methyltransferase promoter methylation equally important in glioblastomas of patients from different continents? A systematic review with meta-analysis

BACKGROUND: O6-methylguanine-DNA methyltransferase (MGMT) is an independent predictor of therapeutic response and potential prognosis in patients with glioblastoma multiforme (GBM). However, its significance of clinical prognosis in different continents still needs to be explored. PATIENTS AND METHO...

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Detalles Bibliográficos
Autores principales: Meng, Wei, Jiang, Yangyang, Ma, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614747/
https://www.ncbi.nlm.nih.gov/pubmed/29033608
http://dx.doi.org/10.2147/CMAR.S140447