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Diagnostic and therapeutic implications of genetic heterogeneity in myeloid neoplasms uncovered by comprehensive mutational analysis

While growing use of comprehensive mutational analysis has led to the discovery of innumerable genetic alterations associated with various myeloid neoplasms, the under-recognized phenomenon of genetic heterogeneity within such neoplasms creates a potential for diagnostic confusion. Here, we describe...

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Detalles Bibliográficos
Autores principales: Choi, Sarah M., Goldenson, Ben, Peterson, Lo Ann, Dinner, Shira, Stein, Brady L., Behdad, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614759/
https://www.ncbi.nlm.nih.gov/pubmed/28975067
http://dx.doi.org/10.1016/j.lrr.2017.09.001