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Glia initiate brain assembly through non-canonical Chimaerin/Furin axon guidance in C. elegans

Brain assembly is hypothesized to begin when pioneer axons extend over non-neuronal cells, forming tracts guiding follower axons. Yet pioneer-neuron identities, their guidance substrates, and their interactions, are not well understood. Here, using time-lapse embryonic imaging, genetics, protein-int...

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Detalles Bibliográficos
Autores principales: Rapti, Georgia, Li, Chang, Shan, Alan, Lu, Yun, Shaham, Shai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614858/
https://www.ncbi.nlm.nih.gov/pubmed/28846083
http://dx.doi.org/10.1038/nn.4630