CB1 Receptor Activation on VgluT2-Expressing Glutamatergic Neurons Underlies Δ(9)-Tetrahydrocannabinol (Δ(9)-THC)-Induced Aversive Effects in Mice

Cannabis can be rewarding or aversive. Cannabis reward is believed to be mediated by activation of cannabinoid CB1 receptors (CB1Rs) on GABAergic neurons that disinhibit dopaminergic neurons in the ventral tegmental area (VTA). However, little is known about the mechanisms underlying cannabis aversi...

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Detalles Bibliográficos
Autores principales: Han, Xiao, He, Yi, Bi, Guo-Hua, Zhang, Hai-Ying, Song, Rui, Liu, Qing-Rong, Egan, Josephine M., Gardner, Eliot L., Li, Jing, Xi, Zheng-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614984/
https://www.ncbi.nlm.nih.gov/pubmed/28951549
http://dx.doi.org/10.1038/s41598-017-12399-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614984/
https://www.ncbi.nlm.nih.gov/pubmed/28951549
http://dx.doi.org/10.1038/s41598-017-12399-z

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