Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes

T-lineage committed precursor thymocytes are screened by a fate-determination process mediated via T cell receptor (TCR) signals for differentiation into distinct lineages. However, it remains unclear whether any antecedent event is required to couple TCR signals with the transcriptional program gov...

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Detalles Bibliográficos
Autores principales: Kojo, Satoshi, Tanaka, Hirokazu, Endo, Takaho A., Muroi, Sawako, Liu, Ye, Seo, Wooseok, Tenno, Mari, Kakugawa, Kiyokazu, Naoe, Yoshinori, Nair, Krutula, Moro, Kazuyo, Katsuragi, Yoshinori, Kanai, Akinori, Inaba, Toshiya, Egawa, Takeshi, Venkatesh, Byrappa, Minoda, Aki, Kominami, Ryo, Taniuchi, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615048/
https://www.ncbi.nlm.nih.gov/pubmed/28951542
http://dx.doi.org/10.1038/s41467-017-00768-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615048/
https://www.ncbi.nlm.nih.gov/pubmed/28951542
http://dx.doi.org/10.1038/s41467-017-00768-1

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