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Interleukin-6 blockade attenuates lung cancer tissue construction integrated by cancer stem cells

In the present study, we successfully generated lung cancer stem cell (CSC)-like cells by introducing a small set of transcription factors into a lung cancer cell line. In addition to properties that are conventionally referred to as CSC properties, the lung induced CSCs exhibited the ability to for...

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Detalles Bibliográficos
Autores principales: Ogawa, Hiroyuki, Koyanagi-Aoi, Michiyo, Otani, Kyoko, Zen, Yoh, Maniwa, Yoshimasa, Aoi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615065/
https://www.ncbi.nlm.nih.gov/pubmed/28951614
http://dx.doi.org/10.1038/s41598-017-12017-y