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Perspectives of the Nrf-2 signaling pathway in cancer progression and therapy

The Nuclear factor erythroid2-related factor2 (Nrf2), a master regulator of redox homoeostasis, is a key transcription factor regulating a wide array of genes for antioxidant and detoxification enzymes. It protects organs from various kinds of toxic insults. On the other hand, activation of Nrf2 is...

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Detalles Bibliográficos
Autores principales: Basak, Priyanka, Sadhukhan, Pritam, Sarkar, Poulami, Sil, Parames C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615147/
https://www.ncbi.nlm.nih.gov/pubmed/28959654
http://dx.doi.org/10.1016/j.toxrep.2017.06.002