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Acute aflatoxin B1 – Induced hepatotoxicity alters gene expression and disrupts lipid and lipoprotein metabolism in rats

In this study, alterations in lipid metabolism associated with acute aflatoxin B1 (AFB1) induced hepatotoxicity and gene expression changes underlying these effects were investigated. Rats were orally administered three doses (0.25 mg/kg, 0.5 mg/kg and 1.0 mg/kg) of AFB1 for seven days; after which...

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Detalles Bibliográficos
Autores principales: Rotimi, Oluwakemi Anuoluwapo, Rotimi, Solomon Oladapo, Duru, Chibueze Uchechukwu, Ebebeinwe, Ogheneworo Joel, Abiodun, Anthonia Obhio, Oyeniyi, Boluwaji Oluwamayowa, Faduyile, Francis Adedayo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615163/
https://www.ncbi.nlm.nih.gov/pubmed/28959666
http://dx.doi.org/10.1016/j.toxrep.2017.07.006