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Kinase-templated abiotic reaction

Protein kinases are quintessential regulators of cellular function. Numerous pathologies are intimately linked to the dysregulated activity of a particular protein kinase. Herein we report a technology based on a proximity-induced chemical transformation that enables the detection and imaging of spe...

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Detalles Bibliográficos
Autores principales: Saarbach, J., Lindberg, E., Folliet, S., Georgeon, S., Hantschel, O., Winssinger, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615226/
https://www.ncbi.nlm.nih.gov/pubmed/28970898
http://dx.doi.org/10.1039/c7sc01416c