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A two-step framework for inferring direct protein-protein interaction network from AP-MS data
BACKGROUND: Affinity purification-mass spectrometry (AP-MS) has been widely used for generating bait-prey data sets so as to identify underlying protein-protein interactions and protein complexes. However, the AP-MS data sets in terms of bait-prey pairs are highly noisy, where candidate pairs contai...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615237/ https://www.ncbi.nlm.nih.gov/pubmed/28950876 http://dx.doi.org/10.1186/s12918-017-0452-y |