A two-step framework for inferring direct protein-protein interaction network from AP-MS data

BACKGROUND: Affinity purification-mass spectrometry (AP-MS) has been widely used for generating bait-prey data sets so as to identify underlying protein-protein interactions and protein complexes. However, the AP-MS data sets in terms of bait-prey pairs are highly noisy, where candidate pairs contai...

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Detalles Bibliográficos
Autores principales: Tian, Bo, Zhao, Can, Gu, Feiyang, He, Zengyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615237/
https://www.ncbi.nlm.nih.gov/pubmed/28950876
http://dx.doi.org/10.1186/s12918-017-0452-y

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