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Hybrid method to solve HP model on 3D lattice and to probe protein stability upon amino acid mutations

BACKGROUND: Predicting protein structure from amino acid sequence is a prominent problem in computational biology. The long range interactions (or non-local interactions) are known as the main source of complexity for protein folding and dynamics and play the dominant role in the compact architectur...

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Detalles Bibliográficos
Autores principales: Guo, Yuzhen, Tao, Fengying, Wu, Zikai, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615245/
https://www.ncbi.nlm.nih.gov/pubmed/28950905
http://dx.doi.org/10.1186/s12918-017-0459-4