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IL-23 and Th17 Disease in Inflammatory Arthritis

IL-23, which is composed of p19 and p40 subunits, is a proinflammatory cytokine that contributes to the formation and maintenance of Th17 cells in inflammatory autoimmune diseases. IL-23 is a human osteoclastogenic cytokine and anti-IL-23 antibody attenuates paw volume and joint destruction in CIA r...

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Detalles Bibliográficos
Autores principales: Yago, Toru, Nanke, Yuki, Kawamoto, Manabu, Kobashigawa, Tsuyoshi, Yamanaka, Hisashi, Kotake, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615274/
https://www.ncbi.nlm.nih.gov/pubmed/28850053
http://dx.doi.org/10.3390/jcm6090081