Development of Antibody–Drug Conjugates Using DDS and Molecular Imaging

Antibody-drug conjugate (ADC), as a next generation of antibody therapeutics, is a combination of an antibody and a drug connected via a specialized linker. ADC has four action steps: systemic circulation, the enhanced permeability and retention (EPR) effect, penetration within the tumor tissue, and...

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Detalles Bibliográficos
Autores principales: Yasunaga, Masahiro, Manabe, Shino, Tsuji, Atsushi, Furuta, Masaru, Ogata, Koretsugu, Koga, Yoshikatsu, Saga, Tsuneo, Matsumura, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615324/
https://www.ncbi.nlm.nih.gov/pubmed/28952557
http://dx.doi.org/10.3390/bioengineering4030078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615324/
https://www.ncbi.nlm.nih.gov/pubmed/28952557
http://dx.doi.org/10.3390/bioengineering4030078

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