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Integrins as Therapeutic Targets: Successes and Cancers

Integrins are transmembrane receptors that are central to the biology of many human pathologies. Classically mediating cell-extracellular matrix and cell-cell interaction, and with an emerging role as local activators of TGFβ, they influence cancer, fibrosis, thrombosis and inflammation. Their ligan...

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Detalles Bibliográficos
Autores principales: Raab-Westphal, Sabine, Marshall, John F., Goodman, Simon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615325/
https://www.ncbi.nlm.nih.gov/pubmed/28832494
http://dx.doi.org/10.3390/cancers9090110