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Integrins as Therapeutic Targets: Successes and Cancers
Integrins are transmembrane receptors that are central to the biology of many human pathologies. Classically mediating cell-extracellular matrix and cell-cell interaction, and with an emerging role as local activators of TGFβ, they influence cancer, fibrosis, thrombosis and inflammation. Their ligan...
Autores principales: | Raab-Westphal, Sabine, Marshall, John F., Goodman, Simon L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615325/ https://www.ncbi.nlm.nih.gov/pubmed/28832494 http://dx.doi.org/10.3390/cancers9090110 |
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