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Integrin Activation Contributes to Lower Cisplatin Sensitivity in MV3 Melanoma Cells by Inducing the Wnt Signalling Pathway

Background: integrins have been associated with the development of chemotherapy resistant tumour cells, mostly those of hematopoietic origin, by mediating the binding to the extracellular matrix. The relevance for solid tumour cells and the underlying mechanisms remain elusive. Methods: using MTT as...

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Detalles Bibliográficos
Autores principales: Piva, Maria B. R., Jakubzig, Bastian, Bendas, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615340/
https://www.ncbi.nlm.nih.gov/pubmed/28926938
http://dx.doi.org/10.3390/cancers9090125