Effects of Cellular Methylation on Transgene Expression and Site-Specific Integration of Adeno-Associated Virus

DNA methylation is a major epigenetic event that affects not only cellular gene expression but that also has the potential to influence bacterial and viral DNA in their host-dependent functions. Adeno-associated virus (AAV) genome contains a high degree of CpG sequences capable of methylation in its...

Descripción completa

Detalles Bibliográficos
Autores principales: Chanda, Diptiman, Hensel, Jonathan A., Higgs, Jerome T., Grover, Rajat, Kaza, Niroop, Ponnazhagan, Selvarangan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615365/
https://www.ncbi.nlm.nih.gov/pubmed/28926997
http://dx.doi.org/10.3390/genes8090232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615365/
https://www.ncbi.nlm.nih.gov/pubmed/28926997
http://dx.doi.org/10.3390/genes8090232

Ejemplares similares