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Effects of Cellular Methylation on Transgene Expression and Site-Specific Integration of Adeno-Associated Virus

DNA methylation is a major epigenetic event that affects not only cellular gene expression but that also has the potential to influence bacterial and viral DNA in their host-dependent functions. Adeno-associated virus (AAV) genome contains a high degree of CpG sequences capable of methylation in its...

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Detalles Bibliográficos
Autores principales:	Chanda, Diptiman, Hensel, Jonathan A., Higgs, Jerome T., Grover, Rajat, Kaza, Niroop, Ponnazhagan, Selvarangan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615365/ https://www.ncbi.nlm.nih.gov/pubmed/28926997 http://dx.doi.org/10.3390/genes8090232

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