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Fish oil prevents excessive accumulation of subcutaneous fat caused by an adverse effect of pioglitazone treatment and positively changes adipocytes in KK mice

Pioglitazone, a thiazolidinedione (TZD), is widely used as an insulin sensitizer in the treatment of type 2 diabetes. However, body weight gain is frequently observed in TZD-treated patients. Fish oil improves lipid metabolism dysfunction and obesity. In this study, we demonstrated suppression of bo...

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Detalles Bibliográficos
Autores principales: Iizuka, Yuzuru, Kim, Hyounju, Nakasatomi, Maki, Izawa, Takuya, Hirako, Satoshi, Matsumoto, Akiyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615378/
https://www.ncbi.nlm.nih.gov/pubmed/28959521
http://dx.doi.org/10.1016/j.toxrep.2015.11.003