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Fish oil prevents excessive accumulation of subcutaneous fat caused by an adverse effect of pioglitazone treatment and positively changes adipocytes in KK mice
Pioglitazone, a thiazolidinedione (TZD), is widely used as an insulin sensitizer in the treatment of type 2 diabetes. However, body weight gain is frequently observed in TZD-treated patients. Fish oil improves lipid metabolism dysfunction and obesity. In this study, we demonstrated suppression of bo...
Autores principales: | Iizuka, Yuzuru, Kim, Hyounju, Nakasatomi, Maki, Izawa, Takuya, Hirako, Satoshi, Matsumoto, Akiyo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615378/ https://www.ncbi.nlm.nih.gov/pubmed/28959521 http://dx.doi.org/10.1016/j.toxrep.2015.11.003 |
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