HM71224, a selective Bruton’s tyrosine kinase inhibitor, attenuates the development of murine lupus

BACKGROUND: Systemic lupus erythematosus (SLE) is associated with B cell hyperactivity, and lupus nephritis (LN), in particular, is promoted by the production of autoantibodies and immune complex deposition. Bruton’s tyrosine kinase (BTK) plays critical roles in B cell receptor-related and Fc recept...

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Detalles Bibliográficos
Autores principales: Kim, Yu-Yon, Park, Ki Tae, Jang, Sun Young, Lee, Kyu Hang, Byun, Joo-Yun, Suh, Kwee Hyun, Lee, Young-Mi, Kim, Young Hoon, Hwang, Kwang Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615432/
https://www.ncbi.nlm.nih.gov/pubmed/28950886
http://dx.doi.org/10.1186/s13075-017-1402-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615432/
https://www.ncbi.nlm.nih.gov/pubmed/28950886
http://dx.doi.org/10.1186/s13075-017-1402-1

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