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Evaluation of sesamol-induced histopathological, biochemical, haematological and genomic alteration after acute oral toxicity in female C57BL/6 mice

The objective of this study was to evaluate organ-wise toxicological effects of sesamol and determine the LD(50) cut-off value and GHS category following acute oral toxicity method OECD 423. An acute oral toxicity study was carried out in female C57BL/6 mice. Observations for physical behaviour and...

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Detalles Bibliográficos
Autores principales: Khan, Shahanshah, Choudhary, Sandeep, Kumar, Arun, Tripathi, Akanchha Mani, Alok, Amit, Adhikari, Jawahar Singh, Rizvi, Moshahid Alam, Chaudhury, Nabo Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615841/
https://www.ncbi.nlm.nih.gov/pubmed/28959616
http://dx.doi.org/10.1016/j.toxrep.2016.03.005