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Facile one-pot four-component synthesis of 3,4-dihydro-2-pyridone derivatives: novel urease inhibitor scaffold

In the current study, a series of 3,4-dihydro-2-pyridone derivatives were synthesized in a one-pot fourcomponent reaction of Meldrum's acid, benzaldehyde derivatives, methyl acetoacetate, and ammonium acetate. SiO2-Pr-SO3H was used as an efficient catalyst for the synthesis of the target compou...

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Detalles Bibliográficos
Autores principales: Hakimi, Arash Modarres, Lashgari, Negar, Mahernia, Shabnam, Ziarani, Ghodsi Mohammadi, Amanlou, Massoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615865/
https://www.ncbi.nlm.nih.gov/pubmed/28974973
http://dx.doi.org/10.4103/1735-5362.213980