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Can allopurinol improve retinopathy in diabetic rats? Oxidative stress or uric acid; which one is the culprit?

Allopurinol, an inhibitor of xanthine oxidase, reduces both plasma uric acid and oxidative stress and shows useful effects on some complications of diabetes. However, it is not defined which of the above mentioned properties are involved. Moreover, to the best of our knowledge no study has been done...

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Detalles Bibliográficos
Autores principales: Goharinia, Mohsen, Zareei, Athar, Rahimi, Mansour, Mirkhani, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615870/
https://www.ncbi.nlm.nih.gov/pubmed/28974978
http://dx.doi.org/10.4103/1735-5362.213985