A proteomic atlas of insulin signalling reveals tissue‐specific mechanisms of longevity assurance

Lowered activity of the insulin/IGF signalling (IIS) network can ameliorate the effects of ageing in laboratory animals and, possibly, humans. Although transcriptome remodelling in long‐lived IIS mutants has been extensively documented, the causal mechanisms contributing to extended lifespan, partic...

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Detalles Bibliográficos
Autores principales: Tain, Luke S, Sehlke, Robert, Jain, Chirag, Chokkalingam, Manopriya, Nagaraj, Nagarjuna, Essers, Paul, Rassner, Mark, Grönke, Sebastian, Froelich, Jenny, Dieterich, Christoph, Mann, Matthias, Alic, Nazif, Beyer, Andreas, Partridge, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615923/
https://www.ncbi.nlm.nih.gov/pubmed/28916541
http://dx.doi.org/10.15252/msb.20177663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615923/
https://www.ncbi.nlm.nih.gov/pubmed/28916541
http://dx.doi.org/10.15252/msb.20177663

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