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Ceramide-1-phosphate protection of cochlear hair cells against cisplatin ototoxicity

BACKGROUND: Ceramide-1-phosphate (C1P) is a phosphorylated form of ceramide. While ceramide is known to be an inducer of apoptosis of cochlear hair cells in cisplatin ototoxicity, little is known about the function of C1P in cochlear diseases. PURPOSE: The present study was designed to examine wheth...

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Detalles Bibliográficos
Autores principales: Le, Quang, Tabuchi, Keiji, Hara, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615927/
https://www.ncbi.nlm.nih.gov/pubmed/28959567
http://dx.doi.org/10.1016/j.toxrep.2016.04.003