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Downregulation of nicotinic and muscarinic receptor function in rats after subchronic exposure to diazinon

Diazinon (DZN) is an organophosphate insecticide which exerts its effect through the inhibition of acetylcholinesterase enzyme (AChE). In this work, we studied the development of tolerance to subchronic p.o. administration of DZN in rats, under both in vivo and in vitro conditions. A group of 20 rat...

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Detalles Bibliográficos
Autores principales: Ivanović, Saša R., Dimitrijević, Blagoje, Ćupić, Vitomir, Jezdimirović, Milanka, Borozan, Sunčica, Savić, Mila, Savić, Djordje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615940/
https://www.ncbi.nlm.nih.gov/pubmed/28959576
http://dx.doi.org/10.1016/j.toxrep.2016.06.002