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Downregulation of nicotinic and muscarinic receptor function in rats after subchronic exposure to diazinon
Diazinon (DZN) is an organophosphate insecticide which exerts its effect through the inhibition of acetylcholinesterase enzyme (AChE). In this work, we studied the development of tolerance to subchronic p.o. administration of DZN in rats, under both in vivo and in vitro conditions. A group of 20 rat...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615940/ https://www.ncbi.nlm.nih.gov/pubmed/28959576 http://dx.doi.org/10.1016/j.toxrep.2016.06.002 |