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Methotrexate and Valproic Acid Affect Early Neurogenesis of Human Amniotic Fluid Stem Cells from Myelomeningocele

Myelomeningocele (MMC) is a severe type of neural tube defect (NTD), in which the backbone and spinal canal do not close completely during early embryonic development. This condition results in serious morbidity and increased mortality after birth. Folic acid significantly reduces, and conversely, f...

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Detalles Bibliográficos
Autores principales: Sahakyan, Vardine, Pozzo, Enrico, Duelen, Robin, Deprest, Jan, Sampaolesi, Maurilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615990/
https://www.ncbi.nlm.nih.gov/pubmed/29056972
http://dx.doi.org/10.1155/2017/6101609