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Prevention of isoniazid toxicity by NAT2 genotyping in Senegalese tuberculosis patients

Isoniazid (INH), recommended by WHO (World Health Organization) in the treatment of tuberculosis (TB), is metabolized primarily by the genetically polymorphic N-acetyltransferase 2 (NAT2) enzyme. The human population is divided into three different phenotypic groups according to acetylation rate: sl...

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Detalles Bibliográficos
Autores principales: Toure, A., Cabral, M., Niang, A., Diop, C., Garat, A., Humbert, L., Fall, M., Diouf, A., Broly, F., Lhermitte, M., Allorge, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5616082/
https://www.ncbi.nlm.nih.gov/pubmed/28959610
http://dx.doi.org/10.1016/j.toxrep.2016.10.004