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Prevention of isoniazid toxicity by NAT2 genotyping in Senegalese tuberculosis patients
Isoniazid (INH), recommended by WHO (World Health Organization) in the treatment of tuberculosis (TB), is metabolized primarily by the genetically polymorphic N-acetyltransferase 2 (NAT2) enzyme. The human population is divided into three different phenotypic groups according to acetylation rate: sl...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5616082/ https://www.ncbi.nlm.nih.gov/pubmed/28959610 http://dx.doi.org/10.1016/j.toxrep.2016.10.004 |