Intrahost Selection Pressures Drive Rapid Dengue Virus Microevolution in Acute Human Infections

Dengue, caused by four dengue virus serotypes (DENV-1 to DENV-4), is a highly prevalent mosquito-borne viral disease in humans. Yet, selection pressures driving DENV microevolution within human hosts (intrahost) remain unknown. We employed a whole-genome segmented amplification approach coupled with...

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Detalles Bibliográficos
Autores principales: Parameswaran, Poornima, Wang, Chunling, Trivedi, Surbhi Bharat, Eswarappa, Meghana, Montoya, Magelda, Balmaseda, Angel, Harris, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5616187/
https://www.ncbi.nlm.nih.gov/pubmed/28910637
http://dx.doi.org/10.1016/j.chom.2017.08.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5616187/
https://www.ncbi.nlm.nih.gov/pubmed/28910637
http://dx.doi.org/10.1016/j.chom.2017.08.003

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