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Intrahost Selection Pressures Drive Rapid Dengue Virus Microevolution in Acute Human Infections
Dengue, caused by four dengue virus serotypes (DENV-1 to DENV-4), is a highly prevalent mosquito-borne viral disease in humans. Yet, selection pressures driving DENV microevolution within human hosts (intrahost) remain unknown. We employed a whole-genome segmented amplification approach coupled with...
Autores principales: | Parameswaran, Poornima, Wang, Chunling, Trivedi, Surbhi Bharat, Eswarappa, Meghana, Montoya, Magelda, Balmaseda, Angel, Harris, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5616187/ https://www.ncbi.nlm.nih.gov/pubmed/28910637 http://dx.doi.org/10.1016/j.chom.2017.08.003 |
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