Increased expression of the tight junction protein TJP1/ZO-1 is associated with upregulation of TAZ-TEAD activity and an adult tissue stem cell signature in carfilzomib-resistant multiple myeloma cells and high-risk multiple myeloma patients

Tight junction protein 1 (TJP1) has recently been proposed as a biomarker to identify multiple myeloma (MM) patients most likely to respond to bortezomib- and carfilzomib-based proteasome inhibitor regimens. Herein we report increased expression of TJP1 during the adaptive response mediating carfilz...

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Detalles Bibliográficos
Autores principales: Riz, Irene, Hawley, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5616201/
https://www.ncbi.nlm.nih.gov/pubmed/28966941
http://dx.doi.org/10.18632/oncoscience.356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5616201/
https://www.ncbi.nlm.nih.gov/pubmed/28966941
http://dx.doi.org/10.18632/oncoscience.356

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